- Original Article
- Nephrology (Genitourinary)
- Changes in the thyroid hormone profiles in children with nephrotic syndrome
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Sun Hee Jung, Jeong Eun Lee, Woo Yeong Chung
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Clin Exp Pediatr. 2019;62(3):85-89. Published online October 4, 2018
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Purpose: We compared thyroid hormone profiles in children with nephrotic syndrome (NS) during the nephrotic phase and after remission.
Methods: This study included 31 pediatric NS patients. The thyroid hormone profiles included serum levels of triiodothyronine (T3), thyroxine (T4), thyroid-stimulating hormone (TSH), and free T4.
Results: Of the 31 patients, 16 (51.6%) showed abnormal thyroid hormone profiles: 6 had overt hypothyroidism, 8... |
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- Serum levels of free insulin-like growth factor-I and
clinical value in healthy children
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Young Hee Chung, Woo Yeong Chung
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Clin Exp Pediatr. 2008;51(1):47-53. Published online January 15, 2008
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Purpose : The serum levels of total insulin-like growth factor (IGF)-I and IGF binding protein (IGFBP)- 3 reflect endogenous growth hormone (GH) secretion in healthy children. Free form of IGF-I which is suggested to have more potent biological action than complex form of IGF-I. The aim of this study is to investigate the serum levels of free IGF-I and its... |
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- The Effect of Angiotensin Converting Enzyme Gene Polymorphism in Children with
Henoch-Schonlein Purpura Nephritis
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Chang Woo Ha, Ji Young Kim, Jeong Nyeo Lee, Jeong Hwa Lee, Woo Yeong Chung
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Clin Exp Pediatr. 2002;45(7):884-890. Published online July 15, 2002
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Purpose : Henoch-Schonlein purpura(HSP) nephritis has been reported to vary from 25 to 50% among HSP patients and is a common cause of chronic glomerulonephritis in children. In our study, we evaluated the distribution and the association of the Insertion/Deletion(I/D) polymorphism of angiotensin converting enzyme(ACE) gene with clinical manifestations, particularly proteinuria in children with HSP nephritis, compared with that in... |
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- Renal Anomalies in Children with Turner Syndrome
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Ji Young Kim, Sun Young Hong, Young Mi Park, Yong Hoon Park, Woo Yeong Chung
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Clin Exp Pediatr. 2002;45(7):891-895. Published online July 15, 2002
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Purpose : The prevalence of renal anomalies in Turner syndrome(TS) has been reported to vary from 33% to 60%. The purpose of this study was to clarify the true incidence of renal malformations in Korean TS.
Methods : We evaluated 33 patients with Turner syndrome diagnosed by karyotype in Inje University Busan Paik hospital and Youngnam University from January 1995.... |
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- Study on Hepatitis B Virus Pre-S/S Gene Mutations in
Children with Chronic Hepatitis B Infection
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Byeong Hee Son, Yeong Hong Park, Woo Yeong Chung
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Clin Exp Pediatr. 2001;44(7):741-751. Published online July 15, 2001
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Purpose : Hepatitis B virus(HBV) with various mutations has been reported. The aims of this study were to investigate the frequency and manifestation of HBV pre-S/S mutations in children with chronic hepatitis B infection.
Methods : Sera from 17 children with chronic hepatitis B infection were analyzed by direct sequencing of polymerase chain reaction amplification of HBV DNA.
Results : Seventeen... |
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- Radiologic Findings of Hands in Turner Syndrome
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Young Sim Han, Moo Young Oh, Young Joon Lee, Woo Yeong Chung
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Clin Exp Pediatr. 2001;44(7):817-822. Published online July 15, 2001
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Purposes : Radiologic findings of hands in Turner syndrome(TS) which have been reported were metacarpal sign(MS), carpal sign(CS), phalangeal sign(PS), osteopenia, and delayed bone maturation. The aim of this study is to evaluate the difference of radiologic findings in TS, idiopathic short stature(ISS), and growth hormone deficiency(GHD).
Methods : Sixty girls with short stature were studied for chromosome analysis, and... |
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- Hepatitis B Virus Pre-S Gene Mutations in Children with Chronic Hepatitis B Infection
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Jae Young Kim, Woo Yeong Chung, Chul Ho Kim
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Clin Exp Pediatr. 2000;43(9):1232-1240. Published online September 15, 2000
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Purpose : The envelope of HBV consists of three polypeptides which are encoded in pre-S/S open reading frame. Three translation initiation sites are present within this pre-S/S open reading frame, i.e. pre-S1, pre-S2, and S, allowing the expression of large, middle and small HBs proteins. The pre-S1 is thought to carry the receptor binding site for viral entry into hepatocyte... |
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- Effects of Growth Hormone Treatment on Alterations of Growth and Bone Metabolism in Rats Induced by Dexamethasone Administration
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Woo Yeong Chung, Jeong Nyu Lee, Hye Kyoung Yoon
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Clin Exp Pediatr. 1999;42(7):991-1002. Published online July 15, 1999
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Purpose : The aim of this study was to investigate the alterations of growth and bone metabolism in SDR induced by dexa administration and to evaluate the effects of GH treatment in dexamethasone(dexa) induced growth and bone metabolism in SDR.
Methods : Forty-five female Sprague-Dawley rats(weight 150-170gm) were divided in 3 groups: Group 1(n=15) received normal saline as control, Group 2(n=15)... |
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- Hepatitis B Virus Precore and Core Promotor Mutations in Children with Chronic Hepatitis B Infection
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Woo Yeong Chung, Jin Kuk Kim, Yeong Hoon Kim, Yeong Hong Park, Chul Ho Kim
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Clin Exp Pediatr. 1999;42(10):1392-1402. Published online October 15, 1999
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Purpose : The aims of this study were to investigate the frequencies and role of hepatitis B virus(HBV) precore and core promotor mutations in children with chronic hepatitis B infection.
Methods : Sera from 31 children with chronic HBV infection were analyzed by direct sequencing of polymerase chain reaction amplification of HBV DNA.
Results : Twenty-nine adr type were analyzed. The mutations... |
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- Original Article
- Effect of Steroid Therapy on Bone Mineral Density in Children with Minimal Change Nephrotic Syndrome
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Byeong Hee Son, Woo Yeong Chung, Chul Ho Kim
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Clin Exp Pediatr. 1996;39(6):822-828. Published online June 15, 1996
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Purpose : Osteoporosis and growth failure have been known one of the serious side
effects of corticosteroid therapy especially in children. This study was designed to evaluate the effect of long-term administration of steroids on bone mineral density(BMD) in children with nephrotic syndrome and its relationship to cumulative steroid dose, the duration of the rapy and sex.
Methods : The BMD of... |
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- Case Report
- A Case of Idiopathic Crescentic Glomerulonephritis
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Jung Keum Park, Sang Il Goo, Woo Yeong Chung, Chul Ho Kim
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Clin Exp Pediatr. 1996;39(1):131-135. Published online January 15, 1996
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We experienced a case of idiopathic crescentic glomerulonephritis in a 10-year-old girl who was admitted to our hospital due to gross hematuria and oliguria for 2 months. The diagnosis was based on the rapidly progressive clinical course to chronic renal failure, positive p-ANCA test and light microscopic findings of diffuse crescents formation in about 80% glomeruli of renal tissue obtained... |
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- Original Article
- Diagnostic Significance of Urinary Growth Hormone Measurement in Patients with Growth Hormone Deficiency
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No Hyun Kim, Woo Yeong Chung, Soon Yong Lee
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Clin Exp Pediatr. 1995;38(8):1124-1131. Published online August 15, 1995
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Purpose : To investigate the diagnostic significance of urinary growth hormone measurement and compare with the urinary GH values in different methods of urine collection, this study was performed in patients with short stature.
Methods : Measurement of urinary GH excretion was performed in 9 children with complete growth hormone deficiency (GCD), in 19 children with partial growth hormone deficiency (GPD)... |
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- Study on Anti-neutrophil Cytoplasmic Antibodies in Children with Henoch-Schölein Purpura
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Shin Jong Lee, Woo Yeong Chung, Chul Ho Kim, Jeong Nyeo Lee
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Clin Exp Pediatr. 1995;38(7):970-975. Published online July 15, 1995
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The presence of IgG, IgA and IgM antineutrophil cytoplasmic antibodies(ANCA) were inves-tigated in 32 children with Henoch-Schölein Purpura(HS purpura), in 14 children with HS pur-pura nephritis who were confirrned by renal biopsy and in 12 control children using flow cytom-etry(FASCan, Beckton-Dickinson, Co, USA) and indirect immunofluorescence technique(Sigma Diagnostics, USA). There were no evidence of IgG, IgA or IgM cytoplasmic ANCA(p-ANCA),... |
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- A Comparative Study o fIntavenous Methylprednisolone Dosage for Treatment of Children with Acute Idiopathic Thrombocytopenic Purpura
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Eun Ju Shin, Yeong Jae Song, Woo Yeong Chung, Tae Gyu Hwang, Soon Yong Lee
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Clin Exp Pediatr. 1995;38(4):513-519. Published online April 15, 1995
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Purpose : It is well known that use of intranenous methylprednisolone(IVMP)for the patients with idiopathic thrombocytopenic purpura(ITP) is not only as effective as use of intravenous gammaglobulin to mincrease platelets quickly, but also the former is less expensive than the latter. As the adequate dosage of IVMP has not been fully elucidated, we have tried to determine it.
Methods : The... |
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- Significance of Urinary Interleukin 6 Level in Mesangial Proliferative Glomerulonephritis in Children
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Byeong Ho Kang, No Hyun Kim, Woo Yeong Chung, Chul Ho Kim, Soon Yong Lee
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Clin Exp Pediatr. 1994;37(7):900-905. Published online July 15, 1994
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By animal experiments in rat, it has been known that Interleukin-6(IL-6) is secreted from renal mesangial cells and is an autocrine growth factor for the proliferation of mesangial cells. According to these facts, several studies have been tried for its clinical usefulness by measuring their serum or urinary IL-6 in glomerulonephritis patients with mesangial proliferation. The authors measured urinary IL-6... |
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- Urinary Vitamin C Loading Test and Therapeutic Effect of Vitamin C in Children with Idiopathic Recurrent Epistaxis
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In Soon Park, Woo Yeong Chung, Soon Yong Lee
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Clin Exp Pediatr. 1993;36(2):266-272. Published online February 15, 1993
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Recurrent epistaxis is not one of rare symptoms in children, the well-known causes of which are anatomical abnormalities of nasal cavity and systemic bleeding tendency. But, in the majority of cases of recurrent epistasix, it is usually very difficult to find out their underlying causes, so that the treatment is only symptomatic control of nasal bleeding whenever epistaxis occurs, but... |
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- Immunohistochemical Studies on Neuroendocrine Markers in Malignant Neuronal Tumors (Neuroblastoma and Ganglioneuroblastoma) in Children
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Woo Yeong Chung, Sun Kyung Lee
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Clin Exp Pediatr. 1992;35(10):1377-1388. Published online October 15, 1992
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The authors studied 24 cases of malignant neuronal tumors, 14 neuroblastomas and 10 ganglioneuroblastomas, immunohistochemically, using antibodies to neuroendocrine markers including neuron specific enolase (NSE), somatostatin, chromogranin, β-endorphin, and adrenocorticotrophic hormone (ACTH). The tissue specimens were obtained by biopsy or autopsy at Pusan National University Hopital and Pusan Paik Hospital from 1980 to 1989. The positive reactivity of markers in... |
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- Case Report
- A Case of Prune Belly Syndrome in Female
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Zu Heo, Eun Joo Shin, Woo Yeong Chung, Soon Yong Lee
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Clin Exp Pediatr. 1992;35(10):1454-1458. Published online October 15, 1992
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We experienced a case of prune belly syndrome in a 2 days old female with deficient abdominal wall musculature and urinary tract anomalies which composed of bilateral multicystic kidney, left vesicoureteral reflux and megaureter with kinking in appearance and marked distended bladder.
On ultrasonographic examination, there were no abnormalities in uterus, vagina and overies.
A review of literatures was also presented briefly. |
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- Original Article
- A Case of Congenital Anterior Urethral Valve.
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Chang Ok Soh, Min Seop Song, Woo Yeong Chung, Soon Young Lee
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Clin Exp Pediatr. 1989;32(12):1749-1751. Published online December 31, 1989
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We experienced a case of congenital anterior urethral valve in a 13-month old male child.
He had recurrent fever and urinary dribbling.
The diagnosis was based on radiologic and cystoscopic findings, and excision of the valve with
suprapubic cystostomy was performed.
A review of literatures was also presented briefly. |
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- A Case of Wilson Disease.
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Cheol Soo Dan, Sang Hoon Lee, Woo Yeong Chung, Soon Yong Lee, Jong Eun Joo, Hye Jae Cho
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Clin Exp Pediatr. 1988;31(11):1502-1508. Published online November 30, 1988
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We have experienced a case of Wilson disease manifesting chronic hepatitis.
The patient, 10-year-old boy, has shown elevated SGOT and SGPT levels since 5 years ago, but no
other specific symptoms of Wilson disease. His younger sister died of fulminant hepatitis (absence of
hepatitis A or B markers) at the age of eight.
The diagnosis was based on the characteristic laboratory data and the... |
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- An Analysis of Incidence Requiring Resuscitation in Full-Term Cesarean Delivered Infants.
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Ewi Seong Seo, Cheol Soo Dan, Woo Yeong Chung, Soon Yong Lee, Goo Hwa Je
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Clin Exp Pediatr. 1987;30(7):722-726. Published online July 31, 1987
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An analysis of incidence requiring resuscitation in relation to the indication of cesarean section in
full-term deliveries were carried out retrospectively during 24 months from January 1984 to December
1985.
The results obtained were as follows.
1) The overall incidence of cesarean delivery was 17.2% (397 cases out of 2,308 total deliveries) and
the rate of full-term was 77.6% of total cesarean deliveries.
2) Among full-term cesarean delivered... |
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- A Case of Congenital Anterior Urethral Diverticulum.
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Young Ho Lee, Gyu Jeon Song, Woo Yeong Chung, Moo Young Oh, Soon Yong Lee
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Clin Exp Pediatr. 1987;30(4):431-434. Published online April 30, 1987
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Recently, we experienced a case of congenital anterior urethral diverticulum in 8-month-old male infant.
He had recurrent fever and urinary dribbling for 3 months.
The diagnosis was based on radiologic and cystoscopic findings, and anterior urethral diverticulectomy was performed.
A review of literatures was also presented briefly.
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- Case Report
- A Case of Combined Esophageal Atresia and Duodenal Atresia.
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Ju Yeong Seo, Cheol Lee, Woo Yeong Chung, Soon Yong Lee, Yeon Soon Kim
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Clin Exp Pediatr. 1985;28(9):912-915. Published online September 30, 1985
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We experienced a case of combined esophageal atresia without tracheoesophageal fistula and duodenal atresia.
Choanal Atresia was also associated. The diagnosis was confirmed by prenatal ultrasonography, abdominal radiography and autopsy. A review of literatures was also presented briefly.
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- A Case of Werdnig Hoffmann Disease.
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Woo Yeong Chung, Cheol Lee, Tai Gyu Hwang, In Soon Park, Soon Young Lee, Jong Eun Joo
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Clin Exp Pediatr. 1985;28(7):726-730. Published online July 31, 1985
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We experienced a case of Werdnig Hoffmann disease in a 1 year 5 month old female child with the complaint of progressive muscular weakness on both lower extremities. Her development had been almost normal since birth and she could stand alone briefly at 12 months of age, but progressive muscular weakness had been apparent since then. Diagnosis was based on... |
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- A Case of Neurofibromatosis associated with Pseudoarthrosis of the Ulna.
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Ju Yeong Seo, Woo Yeong Chung, Soon Yong Lee, Kil Hyun Kim, Yeon Soon Kim
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Clin Exp Pediatr. 1984;27(5):516-520. Published online May 31, 1984
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We experienced a case of neurofibromatosis associated with pseudoarthrosis of the ulna in a 5-year-old boy.
He had multiple cafe-au-lait spots, neurofibromas, and macrocranium with positive family history. A review of literatures was also presented briefly.
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- A Case of Congenital Monocytic Leukemia.
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Woo Yeong Chung, Eue Bon Koo, Hak Jun Ko, Tai Gyu Whang, Soon Yong Lee, Yeon Soon Kim
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Clin Exp Pediatr. 1984;27(10):1022-1027. Published online October 31, 1984
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We experienced a case of congenital monocytic leukemia in a 25 day old female newborn infant. She was admitted because of petechiae, abdominal distension and skin nodules scattered on. whole body. Diagnosis was confirmed with findings of CBC, bone marrow aspiration and cytochemistry. A review of literatures was also presented.
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- A Case of Aplastic Anemia Following Hepatitis.
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Woo Yeong Chung, Seung Won Park, In Soon Park, Chul Ho Kim, Soo Yong Lee
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Clin Exp Pediatr. 1983;26(8):812-815. Published online August 31, 1983
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We experienced a case of aplastic anemia following hepatitis in a 11-year old male child.
He was admitted because of pallor and gum bleedings with an episode of hepatitis 2 months
prior to this admission. On admission CBC showed pancytopenia and there was marked hypocellularity of
all hematopoietic elements in bone marrow aspiration.
Transfusion and treatment with prednisolone and oxymetholone were tried but... |
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- A Case of Gaucher'S Disease In Identical Twins.
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Woo Yeong Chung, Ki Tae Kim, Heon Kyung Lee, Soon Yong Lee, Young Sik Park, Yeon Soon Kim, Soon Ho Kim, Eun Yup Lee
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Clin Exp Pediatr. 1983;26(6):598-605. Published online June 30, 1983
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We experienced a case of Gaucher’s disease of adult type in 3 year 8 month old male
who was one of identical twins with family history of splenomegaly in his two siblings.
Diagnosis was based on clinical pictures such as marked hepatosplenomegaly with anemia
and characteristic pathologic findings of liver and spleen.
There were no specific complications after splenectomy until now.
Review of literatures was... |
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- Original Article
- The Effect of Blue Light and White Light, Continous and Intermittent Phototherapy in the Treatment of Jaundice for the Low Birth Weight Infants.
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Ki Tae Kim, Heon Kyung Lee, Woo Yeong Chung, Soon Youg Lee, Yeon Soon Kim
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Clin Exp Pediatr. 1983;26(4):299-303. Published online April 30, 1983
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The effect of phototherapy was studied between blue and white lights, and continuous and
intermittent regimens in the treatment of jaundice for the low birth weights at Busan
Children’s Hospital from October, 1981 to March, 1982.
The results were as following:
1) The duration of phototherapy necessary to reduce serum bilirubin level below 8 mg/dl
were 58.9 hours with blue light, and 102.3 hours with white... |
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